(Twin Cities Live) This spray is Picaridin 20% and protects against ticks, mosquitos & flies. Picaridin is reported to be as effective as Deet without the irritation. Picaridin is a synthetic compound developed in the 1980s to resemble the natural compound piperine, which is found in the group of plants that are used to produce black pepper. Bugs hate it! These fine mist sprays will protect you from bites for up to 12-hours and come in three different scents; Amber, Orange and Night Sky.